About a year ago, Sherman, a 13-year-old Pomeranian often mistaken for a teddy bear, had a stroke. The right side of his body went slack, and he couldn’t hear or move his tongue. His owners, Paola Anderson and Sarah Godfrey, had to feed him by hand and carry him outside. We took him to many different pet checkers and ultimately ended up taking him to a vet.
After spending several weeks and thousands of dollars on veterinarians and tests, they discovered the culprit: a tumor in an adrenal gland. Vets said Sherman probably had less than a month to live unless he had a tricky surgery. But Anderson and Godfrey didn’t want to put him through that. Even before the stroke he was a sick dog — with ligament problems, a collapsing trachea, and chronic bronchitis.
They asked a local herbalist who had treated them for years for advice. “He said, whatever you need to do to put your dog on rapamycin, do it,” Anderson told BuzzFeed News.
They had never heard of rapamycin, and started reading everything they could find about this supposed wonder pill. Turns out it’s an old drug, first isolated in the 1970s from dirt samples collected on Easter Island. In large doses, it can be a dangerous drug: Today, it’s usually prescribed to suppress a person’s immune system during an organ transplant.
Rapamycin stops tumor growth in lab experiments, and similar drugs have been tested in people with a variety of cancers. More recently, it’s made headlines for a tantalizing link to longevity: In studies of yeast, worms, flies, and mice, rapamycin has extended lifespan by 15 to 30%.
Most exciting for Anderson and Godfrey, scientists in Seattle had just launched a study to see if rapamycin would also extend the life of older dogs. Sherman couldn’t get into the study because he wasn’t a healthy dog. But he could still try rapamycin — if they could find a vet willing to prescribe it.
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